成果筛选
共找到90结果
筛选条件 : Xuedong WANG
Na Li; Chen Wang; Wei Gao; Wenli Li; Binrong Li; Xuedong Wang
Separation and Purification Technology, 2025 356 - EI SCIE

摘要 : An acid gas-induced strategy was proposed to fabricate a series of PCNs with dual-defects and surface hydroxyl group (DDH-PCNs) for photocatalytic H 2 O 2 generation and trace organic contaminants (TrOCs) degradation. The Nv can accelerate the O 2 adsorption and activation by formation a bridge C−O−O−C model. Accompanied cyano groups provide the asymmetric electron distribution for carriers' separation. Moreover, the surficial hydroxyl groups provide more protons for photocatalytic H 2 O 2 production. As a result, the DDH-PCNs showed an excellent photocatalytic H 2 O 2 rate of 5554.6 μmol g −1 h −1 under full spectrum irradiation, and it can also degrade SMX (100 μg/L) completely in 5 min. Notably, the optimal DDH-PCN(1.6) can simultaneously achieve photocatalytic H 2 O 2 production and SMX degradation in a wastewater/alcohol system. The rapid formation of the intermediate superoxide radical (2.44 min −1 ) is the key to above dual functions. Our findings provide profound insights into ·O 2 − manipulation and development of dual functional photocatalytic system towards environmental application.

Ming Gao; Chang Bian; Junxia Wang; Yu Liu; Zhenghao Li; Yutao Zhao
Food Chemistry, 2025 468 - EI SCIE

摘要 : Herein, a "lab-on-an-AIE@Ln/ICP" sensor array was constructed by employing aggregation-induced emission carbon quantum dots (AIE-CQDs) as the guest and Eu/GMP ICP as the host. Based on the antenna effect (AE) and reductive photo-induced electron transfer (r-PET) between CQDs@Eu/GMP ICPs and tetracyclines (TCs), the as-constructed sensor produced satisfactorily dual-emitting fluorescence. By combining pH regulation with principal component analysis (PCA), the underlying fingerprinting patterns realized the specific identification and quantitation of six TCs in animal farm wastewater, milks and milk-derivative products. Through the aggregation-induced quenching of CQDs@Eu/GMP ICPs on test strips, the discernible fluorescence alterations were successfully utilized for developing smartphone-based visual assay. To sum up, the prominent novelty of this study lies in that based on the comprehensive principles of AE and r-PET along with combination of pH-adjustment and PCA, the pioneered sensor assay achieves specifically identifying and sensing individual TCs for their rapid and on-site detection in animal-derived matrices.

Yawei Wang; Xinying Xie; Xiaofei Wang; Chaoyi Wang; Ming Gao; Feiyue Qian
Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 2025 329 - EI SCIE

摘要 : The trace-level detection of tetracyclines (TCs) in food products is essential to ensure food safety and public health. Herein, we prepared the methionine-doped carbon quantum dots (Met-CQDs) using citric acid as the precursor. Met-CQDs exhibited a Gaussian unimodal peak centered at 440 nm in the fluorescent excitation spectrum, along with a remarkable greenish-blue emission and a fluorescent quantum yield of 33.5 %. Furthermore, the presence of TC (the quencher) caused a rapid quenching of the fluorescence of Met-CQDs, accompanying with a color transition from light blue to dark bule as TC concentrations increased. The coloring variation was also detected by the images captured by smartphones and RGB analysis software, facilitating portable detection of TC utilizing Met-CQDs as a fluoroprobe. The findings indicate that the Met-CQDs based fluoroprobe exhibits high selectivity, rapid response (only ∼1 min) according to an "ON-OFF" sensing model. This fluorescence sensing method gave a low detection limit (LOD) of 0.032 μM and excellent linearity for TC in the concentration range of 0.1–500 μM. Also, the smartphone-based fluorescence-visualizing approach displayed good linearity with a LOD of 0.33 μM. The interactions between this fluoroprobe and TC occurred by virtue of both inner filter effect (IFE) and static-quenching principle. The average recovery for TC in the milk, honey, and tap water samples was determined to be 98.46 ± 1.71 % by a fluorometric method. Overall, both fluorometric and RGB approaches demonstrate strong correlation with conventional LC-MS/MS, and thus the as-fabricated Met-CQDs are promising for the preliminary screening of TCs' residues in food products.

Huaxi Zhou; Hui Wang; Huili Wang; Xuedong Wang; Zhaolian Ye; Xiaojun Hu
WAT. RES., 2025 268 - EI SCIE

摘要 : Dissolved black carbon (DBC) with a hyperconjugated structure is ubiquitous in nature, and plays a crucial role in the migration and transformation of environmental contaminants due to its prominent properties of accepting electrons and sorption. However, little is known about the DBC-induced phototransformation of pharmaceutical and personal care products (PPCPs) in natural waters. Herein, the photodegradation kinetics of PPCPs were investigated in DBC solution under simulated solar irradiation and compared with those in Suwannee River natural organic matter (SRNOM) solution. The decay rates for the positively charged PPCPs (mean 1.484 ± 0.041 h -1 ) were significantly higher than those for the negatively charged PPCPs (mean 0.014 ± 0.002 h -1 ) in DBC solution due to the charge interaction. Moreover, the decay rates for the positively charged PPCPs in DBC solution were approximately 3–16 times of those in SRNOM solution due to the discrepant sorption and ability to produce bonded HO • . Finally, a microheterogeneous photodegradation mechanism of HO • -labile PPCPs in DBC solution involving the sorption and subsequent reaction with bonded HO • in the DBC microphase was proposed, which was verified using isopropanol and isopropamide as selective HO • scavengers. This work will provide useful insights into the photochemistry of DBC and also the DBC-involved phototransformation of PPCPs in aquatic environments.

Qiuhui Qian; Qian Pu; Lihang Li; Ji Wu; Guanchen Cheng; Ying Cheng
Journal of Hazardous Materials, 2025 488 - EI SCIE

摘要 : Polylactic acid (PLA) is a biodegradable alternative to traditional plastics due to its excellent biocompatibility. However, PLA is challenging to fully degrade and can easily become microplastics (MPs) in surface water, a process accompanied by aging. This study found that aged PLA (APLA) MPs exhibited increased surface roughness, decreased surface potential, and more oxygen-containing functional groups compared to PLA. Acute exposure to PLA/APLA in zebrafish larvae resulted in sluggish behavior and inhibited neuronal development. Chronic exposure to PLA/APLA in adult zebrafish led to reduced exploratory behavior, poor memory, increased aggression, and neuron loss. Overall, PLA/APLA induced dose-dependent neurotoxicity, with APLA exhibiting greater toxicity than PLA, potentially due to its higher rate of uptake. Additionally, exposure to PLA/APLA led to thinning of the intestinal wall, shortening of villi, and suppression of intestinal neurotransmitter levels, accompanied by alterations in microbial abundance and gut dysbiosis. Meanwhile, supplementation with bile acid, considered as the key regulator in the gut-brain axis, significantly mitigated the neurotoxicity induced by PLA/APLA. These findings confirm that PLA/APLA MPs indeed elicit neurotoxicity via the gut-brain axis and provide scientific evidence for targeted environmental interventions to minimize the adverse ecological impacts of biodegradable MPs.

Chenji Dai; Yaoyao Xu; Libing Ke; Mengjiao Zhu; Rongxiu Deng; Xuedong Wang
ACS Sensors, 2025 -1 - EI SCIE

摘要 : Alzheimer's disease (AD) is characterized by progressive memory loss and cognitive decline, significantly impairing the daily life of elderly individuals. The low abundance of blood-based biomarkers in AD necessitates higher analytical technique requirements. Herein, one novel iridium-based ECL self-enhanced nanoemitter (TPrA@Ir-SiO2) was unprecedentedly reported, and it was further used to construct an ultrasensitive ECL magnetic immunosensor by a multiple-signal amplification strategy to unequally sensitively and accurately detect the AD blood-based biomarker (P-tau181) in this work. The initial signal amplification was accomplished via incorporating a new efficient iridium-based luminophore named Ir(mdq)2(acac) and a corresponding coreactant into silica nanoparticles to successfully obtain TPrA@Ir-SiO2. In addition, the specific and high-affinity interactions between streptavidin and biotin were subsequently employed to further facilitate signal amplification. Based on the advantages of the luminophore itself and the high-affinity interactions between biotin and streptavidin, the corresponding ECL immunosensor proposed in this work exhibited remarkable sensitivity, covering a wide linear range from 0.1 pg/mL to 0.1 μg/mL, and achieved an ultralow limit of detection of 68.58 fg/mL (S/N = 3), and it also exhibited outstanding recovery (98-104%) and RSD (1.92-4.86%) in the detection of serum samples by the spiking method. These remarkable results undoubtedly demonstrate the potential of self-enhanced ECL nanoemitters combined with a synergistic signal amplification strategy bearing streptavidin-biotin in detecting AD blood-based biomarkers, providing accurate and reliable solutions for early diagnosis and monitoring of AD, which would open a new avenue to effectively reduce the burden on AD patients' families and society in the future.

Jin Yan; Lu Fang; Anyu Ni; Miaocui Xi; Jinyun Li; Xin Zhou
Environmental science & technology, 2024 58 (43) - EI SCIE

摘要 : 2-Ethylhexyl diphenyl phosphate (EHDPP), ubiquitously monitored in environmental media, is highly bioaccumulative and may pose long-term risks, even after short-term exposure. In this investigation, larval zebrafish were exposed to 0.05, 0.5, and 5.0 μg/L EHDPP from 4 to 120 h postfertilization (hpf) to examine the long-term neurotoxicity effects of early exposure. Exposure to 5.0 μg/L EHDPP yielded hyperactive locomotor behavior, which was characterized by increased swimming speed, larger turning angles, and heightened sensitivity to light-dark stimulation. The predicted targets of EHDPP (top 100 potential macromolecules) were primarily associated with brain diseases like Alzheimer's disease (AD). Comparisons of differentially expressed genes (DEGs) from AD patients (GSE48350) and RNA-seq data from EHDPP-exposed zebrafish confirmed consistently abnormal regulatory pathways. EHDPP's interaction with M1 and M5 muscarinic acetylcholine receptors likely disrupted calcium homeostasis, leading to mitochondrial dysfunction and neurotransmitter imbalance as well as abnormal locomotor behavior. Especially, 5.0 μg/L EHDPP exposure during early development (4–120 hpf) triggered early- and midstage AD-like symptoms in adulthood (180 dpf), characterized by cognitive confusion, aggression, blood–brain barrier disruption, and mitochondrial damage in brains. These findings provide deep insights into the long-term neurotoxicity effects and Alzheimer's disease risks of early EHDPP exposure at extremely low dosages.

LEI Hui-hui; WANG Xiao-fei; WANG Chao-yi; WANG Ya-wei; WANG Xue-dong; KONG Ling-zhao
Zhongguo Huanjing Kexue/China Environmental Science, 2024 44 (9) - EI

摘要 : A heat-coupled ultrasonic activated persulfate (Heat/US/PDS) oxidation degradation technology of tri (2-chloroethyl) phosphate (TCEP) was established in this study. The reaction parameters were optimized by the central combination design method (CCD) of the response surface (RSM). The reaction parameters of TCEP removal in this system were more moderate (ultrasonic power was 402.5W, temperature was 52.6°C, reaction time was 120min), and the degradation rate of TCEP was predicted to reach 95.3%. Both coexisting ions and humic acids inhibited the removal of TCEP, and the degradation rate of TCEP was 76% in the four water bodies. Radical quenching experiments and EPR analysis showed that SO4·- and ·OH were the main reactive oxygen species. Five possible degradation intermediates of TCEP were detected. Zebrafish embryo exposure experiment showed that TCEP was safe to react in aqueous solution in this system, and the ecotoxicity of TCEP and its possible products to large fleas, algae and fish was evaluated, and the ecotoxicity of degradation products to aquatic organisms was low.

Yuemao Dou; Hongke Bie; Jianhang Duan; Huili Wang; Chunyang Chen; Xuedong Wang
Biosensors & Bioelectronics, 2024 259 - EI SCIE

摘要 : The on-site detection of pyrethroids, particularly type II pyrethroids, remains a challenging task in complex vegetable samples. Herein, a novel method based on naphthalimide was developed to realize the specific detection of type II pyrethroids by hydrolyzing and utilizing the compound m -phenoxybenzaldehyde (3-PBD). Hydrazine group, used as the appropriate moiety, was introduced into the fluorescent dye 1, 8-naphthalimide to construct the fluoroprobe NAP. In the presence of 3-PBD, NAP displayed the prominently enhanced fluorescence and also exhibited high selectivity. This proposed method exhibited high anti-inference effects in complex media, realizing sensitive detection of 3-PBD with linear range of 2.15–800 μM and a low detection limit (LOD) of 0.64 μM. The underlying fluorescence-responsive mechanisms were in-depth elucidated by combining spectral analyses with TD-DFT theoretical calculations. Additionally, a direct and rapid hydrolysis method for deltamethrin in celery was established, achieving a high hydrolysis efficiency of >90% within 15 min. Furthermore, a portable fluorescence sensor (PFS) was developed based on high-power LEDs and photodetectors. PFS supplied a LOD of 2.23 μM for 3-PBD and exhibited comparable stability by a fluorescence spectrometer when detecting celery hydrolysate. Moreover, external power source is not required for PFS operations, thereby enabling rapid and on-site detection by transmitting data to a smartphone via bluetooth. These findings extend the academic knowledge in the field of specific pyrethroids detection and contribute to the development of on-site methods for pesticide residual analyses in food matrices.

Zhongjie Li; Longtian Chen; Yuemao Dou; Huili Wang; Chunyang Chen; Xuedong Wang
Food Chemistry, 2024 449 - EI SCIE

摘要 : Pyrethroids are widely used insecticides worldwide, while their on-site and rapid detection still faces technological challenges. Herein, an innovative detection mechanism was designed for deltamethrin, a typical kind of type II pyrethroids, based on a dual-emitting fluoroprobe consisting of NH 2 -SiQDs and Eu 3+ . Deltamethrin can rapidly hydrolyze into 3-phenoxybenzaldehyde (3-PBD) and react specifically with fluoroprobe, causing fluorescence quenching of SiQDs while maintaining the fluorescent stability of Eu 3+ . Building upon the above fluorescence-responsive principle, SiQDs@Eu 3+ provided satisfactorily dual-emitting signals, realizing the highly-selective and sensitive detection of deltamethrin. Correlation between the surface structure of SiQDs and their absorption spectra was in-depth unraveled by TD-DFT calculation and FT-IR analysis. As for the analytical performance, the recovery and LOD of deltamethrin in lettuce, provided by SiQDs@Eu 3+, were comparable or even superior over conventional chromatographic analysis. Meanwhile, an innovative smartphone-based optical device was developed, which greatly decreased errors caused by the previously reported smartphone-based fluorescence detection.